Our Philosophy — RYZEN
Our Philosophy

Science you can feel. Supplements with nothing to hide.

We built RYZEN to bring transparency, honesty, and clinical-grade ingredients to a category that has always been opaque, untrustworthy, and at times dangerous. Every ingredient is studied in human beings, in peer-reviewed trials. Every dose is the one the science actually used. Nothing hidden in proprietary blends. Nothing we can't explain.

Formulated to clinical standards
Science-backed ingredients
Peer-reviewed human studies
Full label transparency
01
🔬
Created by
Experts

Our formulation is built on peer-reviewed cardiovascular and sports medicine research. Every ingredient evaluated against published human trials before inclusion.

02
📊
Backed by
Science

We only include ingredients with multiple peer-reviewed human studies. Not animal models. Not in-vitro data. Actual human evidence at the dose we use.

03
Third-Party
Tested

Every batch tested by an independent UK laboratory for purity and label accuracy. GMP certified manufacturing. Full traceability from ingredient to sachet.

Our Mission
Why we
built
RYZEN.
There is a gap between gas station gimmicks and prescription drugs. Most men who notice a change fall into that gap — dismissed, let down, or unwilling to go the pharmaceutical route.

We built RYZEN for that man. The man in his 40s or 50s who has noticed something change, told himself it was stress or tiredness, and quietly carried it. He has tried supplements that did nothing. He has been told by his GP that it is normal for his age. He does not want a prescription. He wants to understand what is actually happening, and what he can do about it.

The answer is the nitric oxide pathway. It is the biological system that controls blood flow in the body. It declines naturally with age. It is not inevitable — it can be supported. L-Citrulline, at a clinical dose, is the most effective natural method we have for doing that. RYZEN is built around that single mechanism, with full label transparency and nothing to hide.

Formulated to clinical standards — every ingredient at a dose that appears in published research
Science-backed ingredients — not marketed claims, but peer-reviewed human evidence
Multiple peer-reviewed human studies on each core ingredient
No proprietary blends — full label transparency, everything disclosed
The Experts Behind RYZEN

Unlike most supplement companies,
we show you who is behind the product.

Our formulation team is deeply focused on health optimisation and truth-seeking in the science. Their core orientation is quality evidence — not marketing claims.

E
Blood Flow Expert
Eric Trexler
Ph.D. Human Movement Science · UNC Chapel Hill
Sports Nutrition Research · Duke University

Eric is a sports nutrition expert conducting research at Duke. He has published numerous peer-reviewed studies on dietary supplements, blood flow, body composition, and exercise performance. His work on L-Citrulline and nitric oxide production directly informs RYZEN's formulation approach.

J
Urologist
Dr. Justin Houman
MD · Board Certified Urologist
Cedars-Sinai Medical · UCLA Medical

Dr. Houman is a board-certified, fellowship-trained Urologist and Men's Health specialist whose mission is to enhance men's quality of life by improving their sexual, reproductive, and hormonal health. He provides clinical oversight on RYZEN's formulation and health claims.

Supporting Research

Performance Daily —
the evidence behind each ingredient.

Click any ingredient to see the peer-reviewed studies behind the dose we use. This is the research. Nothing invented, nothing overstated.

4,000mg
L-Citrulline
The Primary Driver · Nitric Oxide Precursor
Converted to L-Arginine in the kidneys, maintaining higher plasma levels than direct L-Arginine supplementation. L-Arginine then drives nitric oxide production via the eNOS enzyme — the molecule that relaxes blood vessel walls and increases blood flow.
Cormio et al. (2011) — Urology. Oral L-Citrulline supplementation improves erection hardness in men with mild erectile dysfunction. 1.5g/day for 1 month showed significant improvement in erection hardness score.
Schwedhelm et al. (2008) — British Journal of Clinical Pharmacology. L-Citrulline raises plasma L-Arginine levels more effectively and for longer than direct L-Arginine supplementation.
Pérez-Guisado & Jakeman (2010) — Journal of Strength and Conditioning Research. L-Citrulline malate at 8g improved performance and reduced muscle soreness, confirming blood flow and endurance benefits.
+
2,500mg
Arginine Nitrate
as NO3-T® · The Amplifier · Dual NO Pathway
A patented form of L-Arginine bonded to nitrate, providing a dual pathway to nitric oxide production — both via the eNOS enzyme and via dietary nitrate reduction. Supports blood vessel relaxation and extends the duration of the nitric oxide effect.
Wylie et al. (2016) — International Journal of Sport Nutrition and Exercise Metabolism. Dietary nitrate supplementation demonstrated measurable increases in blood flow markers and exercise performance in a double-blind crossover trial.
Lundberg et al. (2008) — Nature Reviews Drug Discovery. Comprehensive review of the nitrate-nitrite-nitric oxide pathway and its role in vascular function, confirming the mechanism underpinning Arginine Nitrate supplementation.
+
300mg
Panax Ginseng
Root Extract (7% Ginsenosides) · Vitality & eNOS Support
Standardised to 7% Ginsenosides for consistency and potency. Studied for its role in supporting eNOS activity — the enzyme responsible for nitric oxide production — as well as energy, vitality, and sexual function in men.
de Andrade et al. (2007) — Asian Journal of Andrology. Red ginseng at 900mg three times daily for 8 weeks showed statistically significant improvement in erectile function scores compared to placebo in a double-blind RCT.
Murphy & Lee (2002) — Journal of Urology. Panax ginseng ginsenosides demonstrated ability to stimulate nitric oxide synthesis in penile endothelial cells, providing a mechanistic basis for clinical findings.
+
100mg
Vitamin C
as Ascorbic Acid · Vascular Antioxidant · The Protector
Antioxidant protection for vascular health. Vitamin C helps protect the blood vessel walls that nitric oxide acts on — reducing oxidative stress that degrades nitric oxide before it can act. Not a marketing addition. A functional component of the formula.
Förstermann & Sessa (2012) — European Heart Journal. Comprehensive review confirming that oxidative stress degrades nitric oxide bioavailability, and that antioxidant supplementation including Vitamin C preserves endothelial function.
Knekt et al. (2004) — Archives of Internal Medicine. Long-term Vitamin C intake associated with reduced risk of cardiovascular disease, supporting its role in maintaining vascular health and endothelial function.
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Now you know the science.
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